Melatonin Significantly Reduces COVID-19 Mortality

 

Study Finds Melatonin Significantly Reduces COVID-19 Mortality Dr. Joseph Mercola (Jan 13, 2022) "...In a single-center, open-label, randomized clinical trial, it was observed that melatonin treatment lowered the mortality rate by 93% in severely-infected COVID-19 patients compared with the control group..." -2021 Melatonin Research [Mercola] ...Over the past two years, melatonin has emerged as a surprise weapon against COVID- 19. It's been shown to play a role in viral, bacterial and fungal infections and as early as June 2020, researchers suggested it might be an important adjunct to COVID-19 treatment. According to the authors of that paper, melatonin attenuates several pathological features of COVID-19, including: (Screengrab image) Excessive oxidative stress and inflammation Exaggerated immune response resulting in a cytokine storm Acute lung injury Acute respiratory distress syndrome In October 2020, a scientific review, "Melatonin Potentials Against Viral Infections Including COVID-19: Current Evidence and New Findings," summarized the mechanisms by which melatonin can protect against and ameliorate viral infections such as respiratory syncytial virus, viral hepatitis, viral myocarditis, Ebola, West Nile virus and dengue virus. Based on these collective endings, they hypothesized melatonin may offer similar protection against SARS-CoV-2. One mechanistic basis for this relates to melatonin's effects on p21-activated kinases (PAKs), a family of serine and threonine kinases.